Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1643589 | 0.80 | NPSR1 (0.49) | FFAR4CFTRHTTCA2CA4 | |
| SCHEMBL3341736 | 0.80 | NPSR1 (0.44) | FFAR4CFTRHTTCA2CA4 | |
| SCHEMBL15711849 | 0.79 | HPGD (0.46) | FFAR4CFTRHTTCA2CA4 | |
| SCHEMBL24130743 | 0.79 | HPGD (0.46) | FFAR4CFTRHTTCA2CA4 | |
| Methyl Alcohol SCHEMBL28445602 | 0.77 | CA2 (0.46) | FFAR4CFTRHTTCA2CA4 | |
| SCHEMBL28229202 | 0.76 | CA2 (0.38) | FFAR4CFTRHTTCA2CA4 | |
| SCHEMBL15717372 | 0.76 | TSHR (0.47) | FFAR4CFTRHTTCA2CA4 | |
| Lithium Ion SCHEMBL226387 | 0.75 | CA2 (0.50) | CFTRHTTCA2CA4CA5A | |
| SCHEMBL19274540 | 0.74 | CYP1A2 (0.40) | FFAR4CFTRHTTCYP1A2CYP2A6 | |
| Lithium Ion SCHEMBL28396394 | 0.74 | HTT (0.39) | FFAR4CFTRHTTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230375447-A1 | METHOD FOR ASSAYING A MICRO-OBJECT WITHIN A MICROFLUIDIC DEVICE | BRUKER SPATIAL BIOLOGY, INC. | 2023-11-23 | — | — | US | disclosed |
| US-11802264-B2 | Microfluidic devices for optically-driven convection and displacement, kits and methods thereof | PHENOMEX INC. (US) | 2023-10-31 | — | — | US | disclosed |
| US-11666913-B2 | In situ-generated microfluidic isolation structures, kits and methods of use thereof | BERKELEY LIGHTS, INC (US) | 2023-06-06 | — | — | US | disclosed |
| CN-115894964-A | Photo-curing porous hydrogel cell preparation and preparation method thereof | 四川大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-115850729-A | Light-cured porous hydrogel material and preparation method thereof | 四川大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-115850730-A | Use of photo-cured porous hydrogel material as hemostatic material | 四川大学 | 2023-03-28 | — | — | CN | disclosed |
| US-20230023831-A1 | IN-SITU GENERATED MICROFLUIDIC ASSAY STRUCTURES, RELATED KITS, AND METHODS OF USE THEREOF | BERKLEY LIGHTS, INC. (US) | 2023-01-26 | — | — | US | disclosed |
| US-20210239683-A1 | CELL ENCAPSULATION COMPOSITIONS AND METHODS FOR IMMUNOCYTOCHEMISTRY | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2021-08-05 | — | — | US | disclosed |
| US-20210102150-A1 | Microfluidic Devices for Optically-Driven Convection and Displacement, Kits and Methods Thereof | BRUKER CELLULAR ANALYSIS, INC. | 2021-04-08 | — | — | US | disclosed |
| US-20210011015-A1 | IN SITU-GENERATED MICROFLUIDIC ASSAY STRUCTURES, RELATED KITS, AND METHODS OF USE THEREOF | BRUKER CELLULAR ANALYSIS, INC. | 2021-01-14 | — | — | US | disclosed |
| EP-3737430-A1 | 3D IN VITRO MODELS OF LUNG TISSUE | The Regents Of The University Of Colorado (US) | 2020-11-18 | — | — | EP | disclosed |
| US-10829728-B2 | Microfluidic devices for optically-driven convection and displacement, kits and methods thereof | Berkeley Lights, Inc. (US) | 2020-11-10 | — | — | US | disclosed |
| US-20200347359-A1 | 3D in vitro Models of Lung Tissue | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2020-11-05 | — | — | US | disclosed |
| US-10705082-B2 | In situ-generated microfluidic assay structures, related kits, and methods of use thereof | Berkeley Lights, Inc. (US) | 2020-07-07 | — | — | US | disclosed |
| WO-2019136453-A1 | 3D IN VITRO MODELS OF LUNG TISSUE | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2019-07-11 | — | — | WO | disclosed |
| US-20180298318-A1 | Microfluidic Devices for Optically-Driven Convection and Displacement, Kits and Methods Thereof | BRUKER CELLULAR ANALYSIS, INC. | 2018-10-18 | — | — | US | disclosed |
| US-20170184583-A1 | IN SITU-GENERATED MICROFLUIDIC ASSAY STRUCTURES, RELATED KITS, AND METHODS OF USE THEREOF | BRUKER CELLULAR ANALYSIS, INC. | 2017-06-29 | — | — | US | disclosed |
| US-20170165667-A1 | IN SITU-GENERATED MICROFLUIDIC ISOLATION STRUCTURES, KITS AND METHODS OF USE THEREOF | BRUKER CELLULAR ANALYSIS, INC. | 2017-06-15 | — | — | US | disclosed |