SCHEMBL18940522

SCHEMBL18940522

C=CCOC1OC(C)C(O)C(O)C1OC

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17651742 0.87 AMY1A (0.31) AMY1A
SCHEMBL11668266 0.83
SCHEMBL18940518 0.83 L3MBTL1 (0.36) AMY1A
SCHEMBL13079298 0.83 L3MBTL1 (0.36) AMY1A
SCHEMBL11277134 0.83 L3MBTL1 (0.36) AMY1A
SCHEMBL5670720 0.83 L3MBTL1 (0.36) AMY1A
SCHEMBL2046273 0.83 L3MBTL1 (0.36) AMY1A
SCHEMBL1119069 0.83 L3MBTL1 (0.36) AMY1A
SCHEMBL18305015 0.83 L3MBTL1 (0.36) AMY1A
SCHEMBL26824204 0.83 L3MBTL1 (0.36) AMY1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10962803-B2 Contact lenses with a lubricious coating thereon ALCON INC. (CH) 2021-03-30 US claimed
EP-3746820-A1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON Alcon Inc. (CH) 2020-12-09 EP claimed
US-20190235277-A1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON ALCON INC. (CH) 2019-08-01 US claimed
US-20250223392-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC (CH) 2025-07-10 US disclosed
US-12286501-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2025-04-29 US disclosed
US-20250059330-A1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-02-20 US disclosed
EP-4481478-A2 SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-12-25 EP disclosed
US-12162987-B2 Silicone hydrogel contact lenses ALCON INC. (CH) 2024-12-10 US disclosed
EP-4235274-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-10-09 EP disclosed
US-20240254269-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2024-08-01 US disclosed
US-20240018309-A1 SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2024-01-18 US disclosed
US-20190235277-A1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON ALCON INC. (CH) 2019-08-01 US disclosed
US-20190177460-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2019-06-13 US disclosed
US-10246543-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof NOVARTIS AG (CH) 2019-04-02 US disclosed
US-20180362697-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2018-12-20 US disclosed
US-20180355112-A1 SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2018-12-13 US disclosed
EP-3390498-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF Novartis AG (CH) 2018-10-24 EP disclosed
US-10081697-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof NOVARTIS AG (CH) 2018-09-25 US disclosed
WO-2017103790-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF NOVARTIS AG (CH) 2017-06-22 WO disclosed
US-20170166673-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2017-06-15 US disclosed