Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933402 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTHPGDCYP2C19RECQL | |
| SCHEMBL4073022 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDCYP2C19RECQL | |
| SCHEMBL26526035 | 0.78 | NAPRT (0.48) | ALDH1A1MAPTHPGDCYP2C19RECQL | |
| SCHEMBL9888 | 0.76 | ALDH1A1 (0.86) | ALDH1A1MAPTHPGDCYP2C19RECQL | |
| Hydrochloric Acid SCHEMBL23062930 | 0.74 | ALDH1A1 (0.83) | ALDH1A1MAPTHPGDCYP2C19RECQL | |
| Fluoride SCHEMBL27839088 | 0.74 | ALDH1A1 (0.83) | ALDH1A1MAPTHPGDCYP2C19RECQL | |
| Bromide SCHEMBL28587932 | 0.74 | ALDH1A1 (0.83) | ALDH1A1MAPTHPGDCYP2C19RECQL | |
| SCHEMBL11658250 | 0.74 | ALDH1A1 (0.83) | ALDH1A1MAPTHPGDCYP2C19RECQL | |
| Iodide SCHEMBL7927461 | 0.74 | ALDH1A1 (0.83) | ALDH1A1MAPTHPGDCYP2C19RECQL | |
| SCHEMBL5956218 | 0.74 | HDAC1 (0.58) | ALDH1A1MAPTHPGDCYP2C19RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414571-B1 | MENTHOL-DERIVATIVE COMPOUNDS AND USE THEREOF AS ORAL AND SYSTEMIC ACTIVE AGENTS | COLGATE PALMOLIVE CO (US) | 2017-06-07 | — | — | EP | disclosed |