SCHEMBL18942811

SCHEMBL18942811

CC1(C)c2ccccc2CC(=O)c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.47
BCHE P06276 1/20 0.47
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 4/20 0.44
HPGD P15428 3/20 0.44
HTR2A P28223 1/20 0.43
MAOA P21397 2/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
PGR P06401 6/20 0.40
TDP2 O95551 1/20 0.39
CASP3 P42574 1/20 0.39
CASP7 P55210 1/20 0.39
CASP9 P55211 1/20 0.39
CASP6 P55212 1/20 0.39
CASP8 Q14790 1/20 0.39
MAP3K14 Q99558 1/20 0.39
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
PABPC1 P11940 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9265375 0.81 PGR (0.42) CES1BCHEALDH1A1KDM4EHPGD
SCHEMBL29901667 0.80 HTR2A (0.61) HTR2AMAOAMAOB
SCHEMBL8816862 0.80 HTR2A (0.61) HTR2AMAOAMAOB
SCHEMBL30843843 0.78 HTR2A (0.59) HTR2A
SCHEMBL5740020 0.76 HTR2A (0.48) ALDH1A1HTR2AMAOAMEN1KMT2A
SCHEMBL29522682 0.73 MEN1 (0.52) CES1BCHEALDH1A1KDM4EHTR2A
SCHEMBL12997894 0.73 MEN1 (0.52) CES1BCHEALDH1A1KDM4EHTR2A
SCHEMBL1855552 0.73 MEN1 (0.52) CES1BCHEALDH1A1KDM4EHTR2A
SCHEMBL12997896 0.73 MEN1 (0.52) CES1BCHEALDH1A1KDM4EHTR2A
SCHEMBL31070117 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017095086-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 2017-06-08 WO disclosed