Sugi Predict

Sugi Predict / Compounds / SCHEMBL1855552

SCHEMBL1855552

SCHEMBL1855552

CC1(C)c2ccccc2C(=O)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.52
▸ KMT2A Q03164 4/20 0.52
▸ CDC25B P30305 1/20 0.52
▸ PGR P06401 7/20 0.48
▸ KCNQ2 O43526 3/20 0.46
▸ CYP1A2 P05177 2/20 0.46
▸ CYP3A4 P08684 2/20 0.46
▸ CYP2C9 P11712 2/20 0.46
▸ ALOX15 P16050 2/20 0.46
▸ TSHR P16473 1/20 0.46
▸ PDK2 Q15119 1/20 0.45
▸ PDK4 Q16654 1/20 0.45
▸ KDM4E B2RXH2 2/20 0.43
▸ MAPT P10636 2/20 0.43
▸ THRB P10828 2/20 0.43
▸ RECQL P46063 2/20 0.43
▸ BLM P54132 2/20 0.43
▸ MAOA P21397 2/20 0.43
▸ CES2 O00748 1/20 0.43
▸ APAF1 O14727 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12997896 1.00 MEN1 (0.52) MEN1KMT2ACDC25BPGRKCNQ2
SCHEMBL12997894 1.00 MEN1 (0.52) MEN1KMT2ACDC25BPGRKCNQ2
SCHEMBL29522682 1.00 MEN1 (0.52) MEN1KMT2ACDC25BPGRKCNQ2
SCHEMBL31638323 0.86 PGR (0.46) MEN1KMT2ACDC25BPGRCYP1A2
SCHEMBL10048314 0.84 ELANE (0.58) MEN1KMT2ACDC25BPGRKCNQ2
SCHEMBL15281144 0.84 ELANE (0.58) MEN1KMT2APGRKCNQ2PDK2
SCHEMBL14702110 0.84 PDK2 (0.42) MEN1KMT2APGRPDK2MAPT
SCHEMBL29363404 0.84 HTR2A (0.48) MEN1KMT2APGRPDK2PDK4
SCHEMBL283246 0.84 HTR2A (0.48) MEN1KMT2APGRPDK2PDK4
SCHEMBL883417 0.83 DAO (0.43) MEN1KMT2ACDC25BPGRKCNQ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3943492-B1 TADF MATERIALS COMPRISING 4-(3-(2-(10H-PHENOXAZIN-10-YL)PYRIDIN-5-YL)-9H-CARBAZOL-9-YL)BENZONITRILE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN OLEDS NOCTILUCA S A (PL) 2024-05-08 — — EP claimed
CN-117843460-A Preparation method for producing 10, 10-dimethyl anthrone 中国科学院大连化学物理研究所 2024-04-09 — — CN claimed
CN-117776886-A Preparation method of melitracen hydrochloride intermediate 广东赛烽医药科技有限公司 2024-03-29 — — CN claimed
CN-115417753-B Synthesis method of melitracen and intermediate thereof 重庆西南制药二厂有限责任公司 2024-01-30 — — CN claimed
CN-114685255-B Preparation method of melitracen hydrochloride intermediate 重庆圣华曦药业股份有限公司 2023-12-26 — — CN claimed
CN-115417753-A Synthetic method of melitracen and intermediate thereof 重庆西南制药二厂有限责任公司 2022-12-02 — — CN claimed
CN-114685255-A Preparation method of melitracen hydrochloride intermediate 重庆圣华曦药业股份有限公司 2022-07-01 — — CN claimed
EP-3943492-A1 TADF MATERIALS COMPRISING 4-(3-(2-(10H-PHENOXAZIN-10-YL)PYRIDIN-5-YL)-9H-CARBAZOL-9-YL)BENZONITRILE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN OLEDS Noctiluca S.A. (PL) 2022-01-26 — — EP claimed
CN-108654587-B Process for preparing halogenated hydrocarbons 中国石油化工股份有限公司 2021-09-07 — — CN claimed
CN-109824493-A The preparation method of one kind 10,10- dimethyl anthrone 辽宁博美医药科技有限公司 2019-05-31 — — CN claimed
CN-108654587-A The method for preparing halogenated hydrocarbons 中国石油化工股份有限公司 2018-10-16 — — CN claimed
CN-105061177-A Preparation method of 10,10-dimethylanthrone HUANGSHI LIFUDA MEDICINE CHEMICAL CO LTD 2015-11-18 — — CN claimed
CN-103508940-A 6, 6-disubstituted-6-H-benzo[cd]pyrene derivatives and intermediates, and preparation methods and applications of derivatives and intermediates KUNSHAN VISIONOX DISPLAY TECH 2014-01-15 — — CN claimed
EP-4372057-A2 TADF MATERIALS COMPRISING 4-(3-(2-(10H-PHENOXAZIN-10-YL)PYRIDIN-5-YL)-9H-CARBAZOL-9-YL)BENZONITRILE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN OLEDS Noctiluca S.A. (PL) 2024-05-22 — — EP disclosed
EP-3943492-B1 TADF MATERIALS COMPRISING 4-(3-(2-(10H-PHENOXAZIN-10-YL)PYRIDIN-5-YL)-9H-CARBAZOL-9-YL)BENZONITRILE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN OLEDS NOCTILUCA S A (PL) 2024-05-08 — — EP disclosed
CN-117843460-A Preparation method for producing 10, 10-dimethyl anthrone 中国科学院大连化学物理研究所 2024-04-09 — — CN disclosed
WO-2006116157-A2 DIPEPTIDYL PEPTIDASE-IV INHIBITORS ALANTOS PHARMACEUTICALS HOLDING, INC. (US) 2006-11-02 — — WO disclosed
US-6410754-B1 OPTIC LENSES (GLASSES, SUNGLASSES); HIGH COLORABILITY AND SENSITIVITY TO ACTIVATING IRRADIATION FLAMEL TECHNOLOGIES (FR) 2002-06-25 — — US disclosed
US-20020049341-A1 PHOTOCHROMIC SPIROPYRANS, AND COMPOSITIONS AND ARTICLES CONTAINING SAME FLAMEL TECHNOLOGIES (FR) 2002-04-25 — — US disclosed
US-6162824-A NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS ALLELIX NEUROSCIENCE INC. 2000-12-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020049341-A1 PHOTOCHROMIC SPIROPYRANS, AND COMPOSITIONS AND ARTICLES CONTAINING SAME ALDH1A2, RB1, CRYAA MEN1 3253/4885KMT2A 2768/4885CDC25B 506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.