Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 18/20 | 0.35 |
| ▸ | OXTR | P30559 | 10/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2129942 | 0.86 | AVPR1A (0.48) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL18944344 | 0.78 | P2RX7 (0.40) | AVPR1AOXTRAVPR2 | |
| SCHEMBL18944343 | 0.77 | AVPR1A (0.34) | AVPR1AOXTRAVPR2 | |
| SCHEMBL2631700 | 0.75 | AVPR1A (0.51) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL8266488 | 0.74 | AVPR1A (0.52) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL2129314 | 0.73 | AVPR1A (0.51) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL18944341 | 0.72 | AVPR1A (0.48) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2132179 | 0.70 | AVPR1A (0.56) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2130284 | 0.70 | AVPR1A (0.57) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2129541 | 0.69 | AVPR1A (0.49) | AVPR1AOXTRAVPR2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-B1 | VASOPRESSIN V1A ANTAGONISTS | VANTIA LTD (GB) | 2017-06-07 | — | — | EP | disclosed |