Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616046 | 0.84 | — | — | |
| SCHEMBL18944410 | 0.79 | TAS1R3 (0.33) | TAS1R3TAS1R1 | |
| SCHEMBL12534616 | 0.73 | — | — | |
| SCHEMBL14143879 | 0.71 | TSHR (0.36) | TSHRTAS1R3TAS1R1 | |
| SCHEMBL24894688 | 0.70 | — | — | |
| SCHEMBL19140737 | 0.69 | TSHR (0.35) | TSHRTAS1R3TAS1R1 | |
| SCHEMBL13816390 | 0.69 | TAS1R3 (0.36) | TSHRTAS1R3TAS1R1 | |
| SCHEMBL25448324 | 0.69 | TSHR (0.35) | TSHRTAS1R3TAS1R1 | |
| SCHEMBL27096662 | 0.69 | PTPN1 (0.34) | TSHR | |
| SCHEMBL22785958 | 0.69 | ALDH1A1 (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-B1 | VASOPRESSIN V1A ANTAGONISTS | VANTIA LTD (GB) | 2017-06-07 | — | — | EP | disclosed |