Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19058762 | 0.77 | CYP1A2 (0.46) | MAPT | |
| SCHEMBL29372127 | 0.72 | CYP1A2 (0.38) | MAPT | |
| SCHEMBL21160225 | 0.72 | MAPT (0.33) | MAPT | |
| SCHEMBL13663827 | 0.72 | MAPT (0.36) | MAPT | |
| SCHEMBL19173899 | 0.69 | GNAO1 (0.37) | MAPT | |
| SCHEMBL19038153 | 0.69 | CYP1A2 (0.48) | MAPT | |
| SCHEMBL21859527 | 0.68 | ACE2 (0.39) | MAPTDNM1 | |
| SCHEMBL22500128 | 0.68 | ALDH1A1 (0.47) | MAPT | |
| SCHEMBL11677049 | 0.68 | ALDH1A1 (0.47) | MAPT | |
| SCHEMBL11677487 | 0.68 | ALDH1A1 (0.47) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2661428-B1 | QUINOXALINES AND AZA-QUINOXALINES AS CRTH2 RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2017-06-07 | — | — | EP | disclosed |