Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21719216 | 0.86 | NPC1 (0.35) | L3MBTL1 | |
| SCHEMBL22236494 | 0.86 | NPC1 (0.35) | L3MBTL1 | |
| SCHEMBL13868021 | 0.85 | L3MBTL1 (0.36) | L3MBTL1 | |
| SCHEMBL23051029 | 0.74 | TSHR (0.34) | L3MBTL1 | |
| SCHEMBL10507222 | 0.69 | CNR2 (0.32) | — | |
| SCHEMBL10455028 | 0.68 | CYP2C19 (0.44) | ESR1ESR2 | |
| SCHEMBL419054 | 0.68 | TSHR (0.39) | L3MBTL1 | |
| SCHEMBL22303572 | 0.67 | — | — | |
| Water SCHEMBL28191006 | 0.66 | TSHR (0.38) | L3MBTL1 | |
| SCHEMBL19819811 | 0.66 | AR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10208003-B2 | Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds | KNOPP BIOSCIENCES LLC (US) | 2019-02-19 | — | — | US | disclosed |
| US-20170158648-A1 | SYNTHESIS OF AMINE SUBSTITUTED 4,5,6,7-TETRAHYDROBENZOTHIAZOLE COMPOUNDS | ARETEIA THERAPEUTICS, INC. | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158648-A1 | SYNTHESIS OF AMINE SUBSTITUTED 4,5,6,7-TETRAHYDROBENZOTHIAZOLE COMPOUNDS | TH, PAH, TPST2 | L3MBTL1 4315/4885ESR1 4064/4885ESR2 4230/4885 |
| US-10208003-B2 | Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds | TH, PAH, TPST2 | L3MBTL1 4315/4885ESR1 4064/4885ESR2 4230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.