Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14064086 | 1.00 | TSHR (0.46) | TSHRTDP1TP53POLBGAA | |
| SCHEMBL3175484 | 1.00 | TSHR (0.46) | TSHRTDP1TP53POLBGAA | |
| SCHEMBL282248 | 0.81 | TSHR (0.48) | TSHRTDP1TP53POLBGAA | |
| SCHEMBL9157801 | 0.80 | LAP3 (0.42) | TSHRTDP1TP53POLBGAA | |
| SCHEMBL1711012 | 0.78 | TSHR (0.50) | TSHRTDP1TP53POLBGAA | |
| SCHEMBL10201143 | 0.78 | TSHR (0.50) | TSHRTDP1TP53POLBGAA | |
| Hydrochloric Acid SCHEMBL9004814 | 0.77 | TSHR (0.43) | TSHRTDP1TP53PPARDALDH1A1 | |
| SCHEMBL492011 | 0.77 | LAP3 (0.48) | TSHRTDP1TP53POLBCYP3A4 | |
| SCHEMBL10385714 | 0.77 | LAP3 (0.50) | TSHRTDP1TP53POLBGAA | |
| SCHEMBL1527604 | 0.76 | TSHR (0.48) | TSHRTDP1TP53POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158720-A1 | Antimicrobial Compounds | BIOMERIEUX (FR) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158720-A1 | Antimicrobial Compounds | NGLY1, MRPL21, VIP | TSHR 3023/4885TDP1 3866/4885TP53 2236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.