Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | AHCY | P23526 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18947541 | 0.89 | AHCY (0.43) | ADORA2AADORA2BSLC29A1AHCY | |
| SCHEMBL18947535 | 0.85 | ADORA2A (0.35) | ADORA2AADORA2BSLC29A1LMNATP53 | |
| SCHEMBL12170662 | 0.84 | SLC29A1 (0.38) | ADORA2AADORA2BSLC29A1LMNATP53 | |
| SCHEMBL15203668 | 0.84 | SLC29A1 (0.38) | ADORA2AADORA2BSLC29A1LMNATP53 | |
| SCHEMBL12170660 | 0.82 | AHCY (0.49) | ADORA2AADORA2BSLC29A1AHCY | |
| SCHEMBL18948229 | 0.82 | AHCY (0.49) | ADORA2AADORA2BSLC29A1AHCY | |
| SCHEMBL3654238 | 0.80 | CYP2C19 (0.38) | ADORA2AADORA2BSLC29A1LMNAAHCY | |
| SCHEMBL3654243 | 0.80 | CYP2C19 (0.38) | ADORA2AADORA2BSLC29A1LMNAAHCY | |
| SCHEMBL18947547 | 0.80 | ADORA3 (0.31) | ADORA2AADORA2BLMNATP53 | |
| SCHEMBL18947559 | 0.80 | ADORA2A (0.33) | ADORA2AADORA2BAHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676808-B2 | 2′,4′-substituted nucleosides as antiviral agents | GILEAD PHARMASSET LLC (US) | 2017-06-13 | — | — | US | disclosed |