Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076755 | 0.92 | HTR2B (0.51) | MAPTALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL15276897 | 0.80 | HTR2B (0.53) | MAPTALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL23677205 | 0.80 | HTR2B (0.57) | HTR2BMEN1KMT2ACA12CA1 | |
| SCHEMBL15276896 | 0.79 | LMNA (0.55) | MAPTALDH1A1TSHRHTR2BLMNA | |
| SCHEMBL15276935 | 0.79 | ALDH1A1 (0.50) | MAPTALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL15612991 | 0.78 | HTR2B (0.81) | MAPTALDH1A1GAAHTR2BLMNA | |
| SCHEMBL15076746 | 0.78 | MEN1 (0.51) | MAPTALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL15276919 | 0.77 | MAPT (0.53) | MAPTALDH1A1HTR2BLMNASMN1; SMN2 | |
| SCHEMBL15280078 | 0.77 | LMNA (0.48) | MAPTALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL15276895 | 0.77 | LMNA (0.53) | MAPTALDH1A1TSHRMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-A1 | HEPATITIS B ANTIVIRAL AGENTS | Novira Therapeutics Inc. (US) | 2018-04-25 | — | — | EP | disclosed |
| US-9676747-B2 | Hepatitis B antiviral agents | NOVIRA THERAPEUTICS, INC. (US) | 2017-06-13 | — | — | US | disclosed |