Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | TP53 | P04637 | 6/20 | 0.58 |
| ▸ | IDH1 | O75874 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076818 | 0.91 | MAPT (0.57) | MAPTTP53LMNASMN1; SMN2NPC1 | |
| SCHEMBL18947632 | 0.82 | GSTO1 (0.53) | MAPTTP53IDH1LMNASMN1; SMN2 | |
| SCHEMBL19157049 | 0.82 | GSTO1 (0.57) | MAPTTP53LMNASMN1; SMN2NPC1 | |
| SCHEMBL15076406 | 0.77 | NPC1 (0.60) | MAPTTP53LMNANPC1RAB9A | |
| SCHEMBL18085479 | 0.77 | CNR2 (0.80) | MAPTTP53LMNASMN1; SMN2NPC1 | |
| SCHEMBL21623085 | 0.77 | MAPT (0.57) | MAPTTP53LMNASMN1; SMN2RAB9A | |
| SCHEMBL15076699 | 0.77 | GSTO1 (0.55) | MAPTTP53LMNASMN1; SMN2NPC1 | |
| SCHEMBL15076807 | 0.76 | NPC1 (0.59) | MAPTTP53LMNASMN1; SMN2NPC1 | |
| SCHEMBL15076561 | 0.76 | NPC1 (0.62) | MAPTTP53LMNANPC1RAB9A | |
| SCHEMBL15076741 | 0.76 | GSTO1 (0.63) | MAPTTP53LMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676747-B2 | Hepatitis B antiviral agents | NOVIRA THERAPEUTICS, INC. (US) | 2017-06-13 | — | — | US | disclosed |