Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076406 | 0.94 | NPC1 (0.60) | NPC1RAB9AMAOBMAOAKMT2A | |
| SCHEMBL15076414 | 0.86 | MAPT (0.49) | NPC1RAB9AMAOBKMT2AMAPT | |
| SCHEMBL15076419 | 0.86 | MAPT (0.51) | NPC1RAB9AMAOBKMT2AMAPT | |
| SCHEMBL15076561 | 0.84 | NPC1 (0.62) | NPC1RAB9AMAOBMAOAKMT2A | |
| SCHEMBL21623325 | 0.83 | CA2 (0.61) | NPC1RAB9AMAOBMAOAKMT2A | |
| SCHEMBL15076741 | 0.82 | GSTO1 (0.63) | NPC1RAB9AMAOBMAOAKMT2A | |
| SCHEMBL17465705 | 0.81 | LMNA (0.61) | NPC1RAB9AMAOBMAOAKMT2A | |
| SCHEMBL19157142 | 0.81 | NPC1 (0.65) | NPC1RAB9AMAOBMAOAKMT2A | |
| SCHEMBL15076410 | 0.81 | MAPT (0.55) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL21623225 | 0.80 | CA2 (0.57) | NPC1RAB9AMAOBMAOAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096744-A1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS, INC. (US) | 2013-06-27 | — | — | WO | disclosed |