Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 10/20 | 0.46 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076763 | 0.92 | ENPP2 (0.48) | ENPP2GSTO1LPAR1CYP2C19CYP1A2 | |
| SCHEMBL18947638 | 0.88 | GSTO1 (0.52) | ENPP2GSTO1CYP2C19MAPTALDH1A1 | |
| SCHEMBL18947637 | 0.86 | CYP1A2 (0.50) | ENPP2GSTO1LPAR1CYP2C19CYP1A2 | |
| SCHEMBL18947636 | 0.86 | GSTO1 (0.47) | GSTO1CYP2C19CYP1A2MAPTTP53 | |
| SCHEMBL15076565 | 0.83 | TP53 (0.52) | GSTO1CYP2C19MAPTTP53ALDH1A1 | |
| SCHEMBL15076742 | 0.82 | GSTO1 (0.56) | GSTO1CYP2C19CYP1A2MAPTTP53 | |
| SCHEMBL15076612 | 0.80 | CYP1A2 (0.46) | ENPP2GSTO1LPAR1CYP2C19CYP1A2 | |
| SCHEMBL15076789 | 0.80 | GSTO1 (0.53) | ENPP2GSTO1CYP2C19MAPTTP53 | |
| SCHEMBL21844900 | 0.79 | ENPP2 (0.46) | ENPP2GSTO1LPAR1CYP2C19CYP1A2 | |
| SCHEMBL15076553 | 0.78 | TP53 (0.53) | ENPP2GSTO1CYP2C19MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676747-B2 | Hepatitis B antiviral agents | NOVIRA THERAPEUTICS, INC. (US) | 2017-06-13 | — | — | US | disclosed |