SCHEMBL18947664

SCHEMBL18947664

Cc1ccc(-c2cc(C)c(-c3c4ccccc4c(-c4cc(C)c(-c5ccc(C)c(C(F)(F)F)c5)cc4C)c4ccccc34)cc2C)cc1C

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 4/20 0.42
AR P10275 5/20 0.42
NOTUM Q6P988 1/20 0.37
TRPA1 O75762 1/20 0.36
PDE3B Q13370 1/20 0.35
PDE3A Q14432 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
HSD11B1 P28845 2/20 0.34
PGR P06401 2/20 0.34
HTR7 P34969 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18948610 0.96 S1PR1 (0.45) S1PR1ARNOTUMTRPA1PDE3B
SCHEMBL18947655 0.86 S1PR1 (0.47) S1PR1ARNOTUMPDE3BPDE3A
SCHEMBL18947650 0.85 S1PR1 (0.46) S1PR1ARNOTUMPDE3BPDE3A
SCHEMBL18947659 0.85 S1PR1 (0.46) S1PR1ARNOTUMTRPA1PDE3B
SCHEMBL18947661 0.84 S1PR1 (0.45) S1PR1ARNOTUMPDE3BPDE3A
SCHEMBL18947654 0.84 S1PR1 (0.45) S1PR1ARNOTUMPDE3BPDE3A
SCHEMBL18947658 0.84 S1PR1 (0.45) S1PR1ARNOTUMTRPA1PDE3B
SCHEMBL18948623 0.81 S1PR1 (0.50) S1PR1ARNOTUMTRPA1PDE3B
SCHEMBL18947665 0.81 S1PR1 (0.49) S1PR1ARNOTUMPDE3BPDE3A
SCHEMBL18948629 0.80 S1PR1 (0.47) S1PR1ARNOTUMTRPA1PDE3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9676906-B1 Polymer of poly(arylene ether)s, manufacturing method thereof and polymer light emitting diode with organic light emitting layer made from the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2017-06-13 US disclosed