Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 4/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18949008 | 0.79 | USP30 (0.32) | — | |
| SCHEMBL18947752 | 0.74 | KDM4E (0.41) | MEN1KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL16276339 | 0.61 | MAOB (0.43) | MAPK1NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10737872 | 0.60 | GAA (0.60) | MEN1MAPK1KMT2ANPC1ALDH1A1 | |
| SCHEMBL21400622 | 0.60 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9395688 | 0.60 | EPHX2 (0.43) | KMT2ALMNA | |
| SCHEMBL9699860 | 0.59 | HPGD (0.43) | MEN1KMT2AALDH1A1HTTL3MBTL1 | |
| SCHEMBL9710314 | 0.59 | HPGD (0.43) | MEN1KMT2AALDH1A1HTTL3MBTL1 | |
| SCHEMBL2187527 | 0.59 | ALDH1A1 (0.50) | MEN1MAPK1KMT2ANPC1ALDH1A1 | |
| SCHEMBL21822973 | 0.59 | ATM (0.38) | MEN1MAPK1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |