Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 12/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110731 | 0.81 | SMN1; SMN2 (0.44) | LMNAHPGDMEN1KMT2A | |
| SCHEMBL21043357 | 0.79 | KDM4E (0.46) | KDM4ELMNAALDH1A1HPGDKMT2A | |
| SCHEMBL2233562 | 0.77 | ALDH1A1 (0.42) | KDM4ELMNAALDH1A1L3MBTL1HPGD | |
| SCHEMBL616907 | 0.75 | TDP1 (0.42) | KDM4EALDH1A1L3MBTL1TDP1KDR | |
| SCHEMBL5057172 | 0.75 | KDM4E (0.50) | KDM4ELMNAALDH1A1L3MBTL1HPGD | |
| SCHEMBL18947751 | 0.74 | MEN1 (0.32) | KDM4ELMNALSSALDH1A1L3MBTL1 | |
| SCHEMBL2236603 | 0.72 | KDM4E (0.41) | KDM4ELMNAALDH1A1L3MBTL1TSHR | |
| SCHEMBL614689 | 0.72 | KDM4E (0.68) | KDM4ELMNAALDH1A1L3MBTL1HPGD | |
| SCHEMBL9699860 | 0.72 | HPGD (0.43) | KDM4ELMNALSSALDH1A1L3MBTL1 | |
| SCHEMBL9710314 | 0.72 | HPGD (0.43) | KDM4ELMNALSSALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |