Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14155079 | 0.93 | NR1I2 (0.42) | NR1I2LMNAKDM4EHPGDSLC2A1 | |
| SCHEMBL19003645 | 0.84 | — | — | |
| SCHEMBL22770493 | 0.80 | ADA (0.40) | KDM4E | |
| SCHEMBL21888617 | 0.77 | FAAH (0.37) | NR1I2LMNAKDM4E | |
| SCHEMBL26041690 | 0.77 | FAAH (0.37) | NR1I2LMNAKDM4E | |
| SCHEMBL22193276 | 0.76 | HPGD (0.37) | HPGD | |
| SCHEMBL23491344 | 0.75 | ADA (0.37) | NR1I2GPR84 | |
| SCHEMBL26422953 | 0.75 | SLC2A1 (0.31) | NR1I2SLC2A1 | |
| SCHEMBL28377618 | 0.74 | GPR84 (0.39) | GPR84 | |
| SCHEMBL23870972 | 0.73 | FAAH (0.36) | NR1I2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676780-B2 | Piperazine-substituted [1,2,4]triazolo[1,5-C]quinazolin-5-amine compounds with A2A antagonist properties | MERCK SHARP & DOHME CORP. (US) | 2017-06-13 | — | — | US | disclosed |