Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.36 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5760540 | 0.84 | GFER (0.51) | NPC1ALDH1A1MAPTGFERHSD17B10 | |
| SCHEMBL12598750 | 0.80 | RAB9A (0.38) | NPC1ALDH1A1MAPTGFERRAB9A | |
| SCHEMBL10062532 | 0.78 | RAB9A (0.48) | NPC1ALDH1A1MAPTGFERRAB9A | |
| SCHEMBL890218 | 0.77 | NPC1 (0.50) | NPC1ALDH1A1MAPTGFERHSD17B10 | |
| SCHEMBL91386 | 0.75 | KDM4E (0.62) | NPC1ALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL17130336 | 0.73 | RAB9A (0.58) | NPC1ALDH1A1MAPTGFERRAB9A | |
| SCHEMBL890248 | 0.71 | ALDH1A1 (0.44) | NPC1ALDH1A1MAPTGFERHSD17B10 | |
| SCHEMBL10141714 | 0.71 | ALDH1A1 (0.48) | NPC1ALDH1A1MAPTGFERHSD17B10 | |
| SCHEMBL1470074 | 0.71 | KCNH2 (0.47) | NPC1ALDH1A1MAPTRAB9APOLB | |
| SCHEMBL6760692 | 0.70 | RAB9A (0.56) | NPC1ALDH1A1MAPTGFERRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |