Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.32 |
| ▸ | ACE | P12821 | 3/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634586 | 0.89 | ITGA4 (0.45) | CAPN1ITGA4ITGB7PDE4ACYP11B1 | |
| SCHEMBL13301861 | 0.87 | ACE (0.39) | ITGA4ITGB7ACE | |
| SCHEMBL16173509 | 0.86 | GSK3B (0.35) | CAPN1ITGA4ITGB7ACACBPDE4A | |
| SCHEMBL18526634 | 0.83 | ACACB (0.40) | ACACBCCNE1CDK2GSK3B | |
| SCHEMBL16377060 | 0.82 | CAPN1 (0.36) | CAPN1CHRM5ACE2ACE | |
| SCHEMBL17641842 | 0.82 | CAPN1 (0.36) | CAPN1CHRM5ACE2ACE | |
| SCHEMBL24807994 | 0.78 | KLK5 (0.43) | ITGA4ITGB7ACE | |
| SCHEMBL15729185 | 0.78 | KLK5 (0.43) | ITGA4ITGB7ACE | |
| SCHEMBL10609619 | 0.78 | REN (0.41) | ITGA4ITGB7ACE | |
| SCHEMBL8824831 | 0.77 | KDM4E (0.41) | CAPN1ACACBACE2ACEFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |