Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888855 | 0.82 | CES2 (0.41) | MC4RCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL888866 | 0.82 | CES2 (0.41) | MC4RCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL888790 | 0.82 | CES2 (0.41) | MC4RCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL19578171 | 0.81 | LMNA (0.40) | KMT2ALMNAOPRM1GAA | |
| SCHEMBL8917492 | 0.77 | MC4R (0.41) | MC4RCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL8916563 | 0.77 | MC4R (0.41) | MC4RCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL8915601 | 0.77 | MC4R (0.41) | MC4RCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL8930397 | 0.75 | CES2 (0.43) | MC4RCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL305171 | 0.75 | CES2 (0.43) | MC4RCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL305172 | 0.75 | CES2 (0.43) | MC4RCYP3A4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |