Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20086460 | 0.77 | TP53 (0.32) | TP53 | |
| SCHEMBL22825115 | 0.75 | TP53 (0.31) | TP53 | |
| SCHEMBL15807129 | 0.65 | PTGS2 (0.42) | — | |
| SCHEMBL22156293 | 0.62 | HTR7 (0.43) | — | |
| SCHEMBL23266882 | 0.60 | PTGS2 (0.44) | — | |
| SCHEMBL21565625 | 0.60 | — | — | |
| SCHEMBL21609094 | 0.59 | BRD4 (0.32) | — | |
| SCHEMBL18198118 | 0.58 | PTGS2 (0.34) | — | |
| SCHEMBL9734683 | 0.58 | PTGS2 (0.36) | TP53 | |
| SCHEMBL14606816 | 0.58 | PTGS2 (0.36) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676763-B2 | Method of treating Ebola | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-06-13 | — | — | US | disclosed |