Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.47 |
| ▸ | PGK1 | P00558 | 1/20 | 0.47 |
| ▸ | PGK2 | P07205 | 1/20 | 0.47 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16002754 | 1.00 | HINT1 (0.49) | HINT1ADORA2AADORA3LMNANT5E | |
| SCHEMBL17428139 | 0.90 | ADORA1 (0.59) | ADORA2AADORA3HIF1AADORA2BHSP90B1 | |
| SCHEMBL18950669 | 0.89 | HINT1 (0.52) | HINT1ADORA2AADORA3LMNANT5E | |
| SCHEMBL15993870 | 0.89 | HINT1 (0.52) | HINT1ADORA2AADORA3LMNANT5E | |
| SCHEMBL16002740 | 0.89 | HINT1 (0.52) | HINT1ADORA2AADORA3LMNANT5E | |
| SCHEMBL17417840 | 0.87 | KRAS (0.53) | HINT1NT5E | |
| SCHEMBL16002733 | 0.87 | KRAS (0.53) | HINT1NT5E | |
| SCHEMBL17417839 | 0.87 | KRAS (0.53) | HINT1NT5E | |
| SCHEMBL17428184 | 0.82 | ACHE (0.47) | ADORA2AADORA3PGK1PGK2ADORA1 | |
| SCHEMBL16002755 | 0.82 | ADORA2A (0.57) | HINT1ADORA2AADORA3LMNANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961757-B1 | CELL-PENETRATING OLIGONUCLEOTIDES | OLIGOMER SCIENCES AB (SE) | 2017-06-14 | — | — | EP | disclosed |