Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997019 | 0.83 | HTR6 (0.40) | MAPTALDH1A1SLC9A3L3MBTL1HTT | |
| SCHEMBL4433199 | 0.83 | MAPT (0.39) | MAPTALDH1A1SLC9A3L3MBTL1HTT | |
| SCHEMBL16730754 | 0.70 | HDAC1 (0.40) | — | |
| SCHEMBL18677725 | 0.70 | HDAC1 (0.30) | — | |
| SCHEMBL18950706 | 0.63 | HDAC1 (0.34) | KMT2A | |
| SCHEMBL23511351 | 0.62 | FAAH (0.53) | MAPTALDH1A1 | |
| SCHEMBL13056580 | 0.62 | F2 (0.41) | MAPTALDH1A1MEN1KMT2ASLC9A3 | |
| SCHEMBL23511352 | 0.62 | MEN1 (0.47) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL30945265 | 0.62 | MEN1 (0.47) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL15384767 | 0.61 | SMN1; SMN2 (0.51) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3179252-A1 | COVALENT TETHERING OF FUNCTIONAL GROUPS TO PROTEINS AND SUBSTRATES THEREFOR | Promega Corporation (US) | 2017-06-14 | — | — | EP | disclosed |