Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | NT5E | P21589 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403233 | 0.96 | GSTP1 (0.41) | GSTP1ALBMEN1USP2ALDH1A1 | |
| SCHEMBL4403236 | 0.92 | GSTP1 (0.45) | GSTP1ALBMEN1USP2ALDH1A1 | |
| SCHEMBL9965287 | 0.90 | ALB (0.39) | GSTP1ALBMEN1USP2ALDH1A1 | |
| SCHEMBL13881238 | 0.89 | GSTP1 (0.46) | GSTP1ALBMEN1USP2ALDH1A1 | |
| SCHEMBL13193883 | 0.88 | GSTP1 (0.43) | GSTP1ALBMEN1USP2ALDH1A1 | |
| SCHEMBL12951612 | 0.87 | GSTP1 (0.42) | GSTP1ALBMEN1USP2ALDH1A1 | |
| SCHEMBL12964684 | 0.86 | ALB (0.44) | GSTP1ALBMEN1USP2ALDH1A1 | |
| SCHEMBL13435046 | 0.83 | KMT2A (0.53) | GSTP1MEN1USP2ALDH1A1LMNA | |
| SCHEMBL4437789 | 0.83 | HPGD (0.40) | GSTP1MEN1ALDH1A1MAPTHTT | |
| SCHEMBL12671652 | 0.82 | HDAC6 (0.33) | GSTP1ALBMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3179252-A1 | COVALENT TETHERING OF FUNCTIONAL GROUPS TO PROTEINS AND SUBSTRATES THEREFOR | Promega Corporation (US) | 2017-06-14 | — | — | EP | disclosed |