Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31343967 | 0.94 | GSTP1 (0.58) | KMT2AHTTMEN1USP2ALDH1A1 | |
| SCHEMBL12951612 | 0.88 | GSTP1 (0.42) | KMT2AHTTMEN1USP2ALDH1A1 | |
| SCHEMBL30112575 | 0.87 | NT5E (0.41) | KMT2AHTTMEN1USP2ALDH1A1 | |
| SCHEMBL24942496 | 0.87 | NT5E (0.41) | KMT2AHTTMEN1USP2ALDH1A1 | |
| SCHEMBL4403233 | 0.87 | GSTP1 (0.41) | KMT2AHTTMEN1USP2ALDH1A1 | |
| SCHEMBL25457745 | 0.84 | KMT2A (0.55) | KMT2AHTTMEN1USP2ALDH1A1 | |
| SCHEMBL4437792 | 0.84 | GSTP1 (0.59) | KMT2AHTTMEN1USP2ALDH1A1 | |
| SCHEMBL18526322 | 0.84 | NT5E (0.41) | KMT2AHTTMEN1USP2ALDH1A1 | |
| SCHEMBL18950720 | 0.83 | GSTP1 (0.38) | KMT2AHTTMEN1USP2ALDH1A1 | |
| SCHEMBL23291866 | 0.83 | NT5E (0.38) | KMT2AHTTMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100075394-A1 | Method of Crosslinking Two Objects of Interest | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075394-A1 | Method of Crosslinking Two Objects of Interest | CD2BP2, FYN, ILK | KMT2A 3466/4885HTT 3333/4885MEN1 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.