Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16153101 | 0.89 | HDAC6 (0.33) | HPGDRAB9ASMN1; SMN2HTTNPC1 | |
| SCHEMBL4403236 | 0.86 | GSTP1 (0.45) | HTTHDAC6GSTP1KMT2AMEN1 | |
| SCHEMBL4403233 | 0.86 | GSTP1 (0.41) | HTTHDAC6GSTP1KMT2AMEN1 | |
| SCHEMBL12671652 | 0.86 | HDAC6 (0.33) | HPGDRAB9ASMN1; SMN2NPC1HDAC3 | |
| SCHEMBL15976894 | 0.85 | HDAC3 (0.33) | HPGDSMN1; SMN2HDAC3HDAC1HDAC6 | |
| SCHEMBL16503905 | 0.84 | LMNA (0.33) | HPGDSMN1; SMN2HDAC3HDAC1HDAC6 | |
| SCHEMBL13193883 | 0.84 | GSTP1 (0.43) | HTTHDAC6GSTP1KMT2AMEN1 | |
| SCHEMBL12018901 | 0.84 | HDAC6 (0.34) | RAB9ASMN1; SMN2NPC1HDAC3HDAC1 | |
| SCHEMBL13881238 | 0.84 | GSTP1 (0.46) | HPGDHTTHDAC6GSTP1KMT2A | |
| SCHEMBL14330482 | 0.83 | HDAC3 (0.33) | HPGDSMN1; SMN2HDAC3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168405-B2 | Covalent tethering of functional groups to proteins and substrates therefor | PROMEGA CORPORATION (US) | 2012-05-01 | — | — | US | disclosed |