Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | PNLIP | P16233 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1895080 | 1.00 | MAPT (0.47) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL1895082 | 1.00 | MAPT (0.47) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL1887493 | 0.91 | MEN1 (0.48) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL1887496 | 0.91 | MEN1 (0.48) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL1887498 | 0.91 | MEN1 (0.48) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL1895191 | 0.89 | MAPT (0.47) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL1895189 | 0.89 | MAPT (0.47) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL1890302 | 0.88 | MAOB (0.51) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL1890304 | 0.88 | MAOB (0.51) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL1890301 | 0.88 | MAOB (0.51) | MAPTMEN1KMT2ALMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110117649-A1 | Catalytic enantioselective synthesis of flavanones and chromanones | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-05-19 | — | — | US | disclosed |
| US-7851640-B2 | Catalytic enantioselective synthesis of flavanones and chromanones | NORTHWESTERN UNIVERSITY (US) | 2010-12-14 | — | — | US | disclosed |
| US-20090259055-A1 | Catalytic enantioselective synthesis of flavanones and chromanones | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259055-A1 | Catalytic enantioselective synthesis of flavanones and chromanones | RNGTT, CDK20, TBXAS1 | MAPT 4627/4885MEN1 4332/4885KMT2A 2596/4885 |
| US-20110117649-A1 | Catalytic enantioselective synthesis of flavanones and chromanones | RNGTT, CDK20, TBXAS1 | MAPT 4627/4885MEN1 4332/4885KMT2A 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.