Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1894598 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1PKMSIGMAR1L3MBTL1 | |
| SCHEMBL1899276 | 0.71 | EPHX2 (0.34) | SIGMAR1EPHX2 | |
| SCHEMBL28829906 | 0.68 | HTR2C (0.40) | ALDH1A1SIGMAR1CNR2GAAPOLB | |
| SCHEMBL3149135 | 0.68 | KDM1A (0.38) | SMN1; SMN2ALDH1A1PKMSIGMAR1L3MBTL1 | |
| SCHEMBL1906430 | 0.67 | SLC6A4 (0.35) | TSHRMAPT | |
| SCHEMBL1902602 | 0.66 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1POLBMAPTHSD11B1 | |
| SCHEMBL13651783 | 0.64 | ALDH1A1 (0.39) | ALDH1A1SIGMAR1L3MBTL1GAAPOLB | |
| SCHEMBL1894852 | 0.63 | HSD11B1 (0.55) | SMN1; SMN2ALDH1A1POLBCHRNA7MAPT | |
| SCHEMBL6872023 | 0.62 | PROKR1 (0.44) | GAACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL2169585 | 0.61 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1CNR2MAPTHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322505-A1 | 1-ADAMANTYLAZETIDIN-2-ONE DERIVATIVE AND PHARMACEUTICAL PREPARATION COMPRISING SAME | Kowa Company, Ltd. (JP) | 2011-05-18 | — | — | EP | claimed |