Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18951616 | 0.88 | NPC1 (0.44) | GABRA1GABRB2NPC1RAB9AKDM4E | |
| SCHEMBL9468018 | 0.86 | NPC1 (0.46) | GABRA1GABRB2NPC1RAB9AKDM4E | |
| SCHEMBL19200635 | 0.85 | HMGCR (0.34) | NPC1RAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL27929913 | 0.78 | NPC1 (0.36) | GABRA1GABRB2NPC1RAB9AKDM4E | |
| SCHEMBL195720 | 0.77 | NPC1 (0.36) | GABRA1GABRB2NPC1RAB9AKDM4E | |
| SCHEMBL29400095 | 0.77 | NPC1 (0.36) | GABRA1GABRB2NPC1RAB9AKDM4E | |
| SCHEMBL7564694 | 0.75 | NPC1 (0.35) | NPC1RAB9APOLB | |
| SCHEMBL196019 | 0.73 | NPC1 (0.50) | GABRA1GABRB2NPC1RAB9AKDM4E | |
| SCHEMBL29401488 | 0.73 | NPC1 (0.50) | GABRA1GABRB2NPC1RAB9AKDM4E | |
| SCHEMBL12387038 | 0.73 | NPC1 (0.59) | GABRA1GABRB2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3178898-A1 | ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORPTIVITY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME | Miyoshi Oil & Fat Co., Ltd. (JP) | 2017-06-14 | — | — | EP | disclosed |