Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566053 | 0.88 | NPC1 (0.44) | NPC1RAB9APOLB | |
| SCHEMBL7568491 | 0.87 | NPC1 (0.37) | NPC1RAB9A | |
| SCHEMBL27623462 | 0.83 | RAB9A (0.42) | NPC1RAB9APOLB | |
| SCHEMBL74494 | 0.81 | KDM4E (0.35) | NPC1RAB9APOLB | |
| SCHEMBL7739367 | 0.81 | MCL1 (0.32) | NPC1RAB9A | |
| SCHEMBL74867 | 0.80 | NPC1 (0.33) | NPC1RAB9APOLB | |
| SCHEMBL74481 | 0.79 | NPC1 (0.33) | NPC1RAB9A | |
| SCHEMBL9259895 | 0.78 | PTPN1 (0.44) | NPC1RAB9A | |
| SCHEMBL9258557 | 0.75 | NPC1 (0.43) | NPC1RAB9A | |
| SCHEMBL18951663 | 0.75 | GABRA1 (0.38) | NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855393-B1 | BISBENZOTRIAZOLYLPHENOLS | OTSUKA KAGAKU KK (JP) | 2002-08-14 | — | — | EP | claimed |
| US-5922882-A | ULTRAVIOLET RADIATION ABSORBER; COPOLYMERIZATION COMPONENT OF BISBENZOTRIAZOLE COMPRISING A COPOLYCARBONATE, A COPOLYESTER, A COPOLYURETHANE AND A COPOLYURETHANEURA | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-07-13 | — | — | US | disclosed |