Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | PLG | P00747 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 15/20 | 0.54 |
| ▸ | KDM4A | O75164 | 13/20 | 0.54 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.54 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.54 |
| ▸ | KDM5A | P29375 | 2/20 | 0.54 |
| ▸ | KDM7A | Q6ZMT4 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18951933 | 0.93 | LMNA (0.57) | MEN1ALDH1A1PLGLMNATHRB | |
| SCHEMBL18970370 | 0.91 | KDM4C (0.66) | MEN1ALDH1A1PLGLMNATHRB | |
| SCHEMBL18952066 | 0.91 | KDM4C (0.66) | MEN1ALDH1A1PLGLMNATHRB | |
| SCHEMBL18951965 | 0.87 | KDM4A (0.66) | MEN1ALDH1A1PLGLMNATHRB | |
| SCHEMBL18951929 | 0.87 | KDM4A (0.66) | MEN1ALDH1A1PLGLMNATHRB | |
| SCHEMBL14981963 | 0.85 | KDM4A (0.62) | MEN1ALDH1A1PLGLMNATHRB | |
| SCHEMBL9835318 | 0.81 | KDM5A (0.71) | MEN1ALDH1A1ALOX15KMT2AKDM4C | |
| SCHEMBL14322257 | 0.79 | LMNA (1.00) | MEN1ALDH1A1PLGLMNATHRB | |
| Pimelic Acid SCHEMBL21465298 | 0.79 | LMNA (1.00) | MEN1ALDH1A1PLGLMNATHRB | |
| Adipic Acid SCHEMBL10591067 | 0.79 | LMNA (1.00) | MEN1ALDH1A1PLGLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250025582-A1 | LIGANDS AND THEIR USE | THE UNIVERSITY OF SYDNEY (AU) | 2025-01-23 | — | — | US | disclosed |
| EP-4267204-A1 | LIGANDS AND THEIR USE | The University Of Sydney (AU) | 2023-11-01 | — | — | EP | disclosed |
| CN-116710437-A | Ligands and uses thereof | 悉尼大学 | 2023-09-05 | — | — | CN | disclosed |
| WO-2022133537-A1 | LIGANDS AND THEIR USE | THE UNIVERSITY OF SYDNEY (AU) | 2022-06-30 | — | — | WO | disclosed |
| WO-2017096430-A1 | HYDROXAMIC ACID-BASED COMPOUNDS | THE UNIVERSITY OF SYDNEY (AU) | 2017-06-15 | — | — | WO | disclosed |
| WO-2017096430-A1 | HYDROXAMIC ACID-BASED COMPOUNDS | THE UNIVERSITY OF SYDNEY (AU) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250025582-A1 | LIGANDS AND THEIR USE | PAICS, CD47, CD74 | MEN1 648/4885ALDH1A1 4389/4885PLG 778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.