SCHEMBL18951981

SCHEMBL18951981

Cn1ccc(OBOc2ccn(C)c2)c1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
INMT O95050 2/20 0.33
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3258502 0.75
SCHEMBL12020327 0.73
SCHEMBL27485169 0.73
SCHEMBL21965344 0.70 CA12 (0.34) INMTCA12CA1CA2CA9
SCHEMBL20667265 0.70 BRD4 (0.39) INMTCA12CA1CA2CA9
SCHEMBL14368169 0.68
SCHEMBL20829441 0.66 NUDT1 (0.33) CA12CA1CA2CA9
SCHEMBL570057 0.64
SCHEMBL24806045 0.63 ALDH1A1 (0.59) CA12CA1CA2CA9
SCHEMBL20665985 0.63 ELANE (0.50) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109748915-B Inhibitors of influenza virus replication and methods of use and uses thereof 广东东阳光药业有限公司 2021-03-26 CN disclosed
CN-108276401-B Inhibitors of influenza virus replication and uses thereof 广东东阳光药业有限公司 2020-12-22 CN disclosed
EP-3362451-A1 INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF Sunshine Lake Pharma Co., Ltd. (CN) 2018-08-22 EP disclosed
WO-2018127096-A1 INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2018-07-12 WO disclosed
WO-2017097234-A1 INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2017-06-15 WO disclosed