Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 12/20 | 0.48 |
| ▸ | FLT1 | P17948 | 11/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658614 | 0.77 | KDR (0.46) | KDRFLT1MAOBKMT2AHTR6 | |
| SCHEMBL26703942 | 0.77 | HTR6 (0.58) | KDRFLT1KMT2AHTR6 | |
| SCHEMBL18967932 | 0.77 | FLT1 (0.52) | KDRFLT1MAOBHTR6 | |
| SCHEMBL18939101 | 0.77 | CYP11B1 (0.52) | — | |
| SCHEMBL18939141 | 0.77 | FLT1 (0.54) | KDRFLT1MAOB | |
| SCHEMBL18952010 | 0.76 | CYP3A4 (0.41) | KDRFLT1MAOBKMT2AHTR6 | |
| SCHEMBL30167818 | 0.76 | FLT1 (0.64) | KDRFLT1MAOBHDAC1HDAC2 | |
| SCHEMBL30167809 | 0.76 | LIMK2 (0.49) | KDRFLT1KMT2AHTR6 | |
| SCHEMBL30167767 | 0.73 | HTR6 (0.45) | KDRFLT1KMT2AHTR6 | |
| SCHEMBL18967486 | 0.73 | FLT1 (0.47) | KDRFLT1MAOBHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386977-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | NAEJA-RGM Pharmaceuticals ULC (CA) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017096472-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | NAEJA-RGM PHARMACEUTICALS INC. (CA) | 2017-06-15 | — | — | WO | disclosed |