Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 11/20 | 0.41 |
| ▸ | FLT1 | P17948 | 10/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658614 | 0.77 | KDR (0.46) | KDRFLT1KMT2AMAOBHTR6 | |
| SCHEMBL26703942 | 0.77 | HTR6 (0.58) | KDRFLT1KMT2AHTR6KDM4C | |
| SCHEMBL18939101 | 0.77 | CYP11B1 (0.52) | — | |
| SCHEMBL18952009 | 0.76 | KDR (0.48) | KDRFLT1KMT2AMAOBHTR6 | |
| SCHEMBL30167767 | 0.73 | HTR6 (0.45) | KDRFLT1KMT2AHTR6KDM4C | |
| SCHEMBL18939136 | 0.72 | PLAU (0.67) | KDRFLT1KMT2AHTR6HDAC1 | |
| SCHEMBL28927893 | 0.71 | FLT1 (0.40) | KDRFLT1MAOBHTR6SLC22A12 | |
| SCHEMBL30167726 | 0.71 | NAMPT (0.45) | KDRFLT1KMT2AHTR6 | |
| SCHEMBL3434482 | 0.70 | LMNA (0.55) | CYP3A4TSHRKMT2A | |
| SCHEMBL18952014 | 0.69 | FLT1 (0.44) | KDRFLT1MAOBHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386977-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | NAEJA-RGM Pharmaceuticals ULC (CA) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017096472-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | NAEJA-RGM PHARMACEUTICALS INC. (CA) | 2017-06-15 | — | — | WO | disclosed |