Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21457834 | 0.78 | SLC1A2 (0.37) | TSHR | |
| SCHEMBL11294177 | 0.71 | ALDH1A1 (0.33) | ALDH1A1TRPM8KDM4ETDP1LMNA | |
| SCHEMBL23092062 | 0.69 | F10 (0.34) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL18952297 | 0.69 | UGT2B7 (0.38) | ALDH1A1TRPM8NPSR1L3MBTL1TSHR | |
| SCHEMBL11616835 | 0.69 | ALDH1A1 (0.38) | ALDH1A1TRPM8NPSR1L3MBTL1UGT2B7 | |
| SCHEMBL18952219 | 0.69 | SMN1; SMN2 (0.34) | ALDH1A1L3MBTL1TSHRUGT2B7CYP2D6 | |
| SCHEMBL1185736 | 0.68 | ALDH1A1 (0.36) | ALDH1A1NPSR1L3MBTL1KDM4ELMNA | |
| SCHEMBL28723335 | 0.68 | KDM4E (0.36) | ALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL18952295 | 0.68 | SMN1; SMN2 (0.33) | ALDH1A1L3MBTL1TSHRKDM4ELMNA | |
| SCHEMBL18952221 | 0.68 | SMN1; SMN2 (0.36) | ALDH1A1TSHRUGT2B7KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640460-B2 | Substituted cyclopentyl- and cyclohexyl-derivatives useful for perfumery | GIVAUDAN SA (CH) | 2020-05-05 | — | — | US | claimed |
| EP-3386940-B1 | SUBSTITUTED CYCLOPENTYL- AND CYCLOHEXYL-DERIVATIVES USEFUL FOR PERFUMERY | GIVAUDAN SA (CH) | 2019-10-16 | — | — | EP | claimed |
| US-20180346412-A1 | SUBSTITUTED CYCLOPENTYL- AND CYCLOHEXYL-DERIVATIVES USEFUL FOR PERFUMERY | GIVAUDAN SA (CH) | 2018-12-06 | — | — | US | claimed |
| EP-3386940-A1 | SUBSTITUTED CYCLOPENTYL- AND CYCLOHEXYL-DERIVATIVES USEFUL FOR PERFUMERY | Givaudan S.A. (CH) | 2018-10-17 | — | — | EP | claimed |
| WO-2017097884-A1 | SUBSTITUTED CYCLOPENTYL- AND CYCLOHEXYL-DERIVATIVES USEFUL FOR PERFUMERY | GIVAUDAN SA (CH) | 2017-06-15 | — | — | WO | claimed |
| US-10640460-B2 | Substituted cyclopentyl- and cyclohexyl-derivatives useful for perfumery | GIVAUDAN SA (CH) | 2020-05-05 | — | — | US | disclosed |
| EP-3386940-B1 | SUBSTITUTED CYCLOPENTYL- AND CYCLOHEXYL-DERIVATIVES USEFUL FOR PERFUMERY | GIVAUDAN SA (CH) | 2019-10-16 | — | — | EP | disclosed |
| US-20180346412-A1 | SUBSTITUTED CYCLOPENTYL- AND CYCLOHEXYL-DERIVATIVES USEFUL FOR PERFUMERY | GIVAUDAN SA (CH) | 2018-12-06 | — | — | US | disclosed |
| EP-3386940-A1 | SUBSTITUTED CYCLOPENTYL- AND CYCLOHEXYL-DERIVATIVES USEFUL FOR PERFUMERY | Givaudan S.A. (CH) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017097884-A1 | SUBSTITUTED CYCLOPENTYL- AND CYCLOHEXYL-DERIVATIVES USEFUL FOR PERFUMERY | GIVAUDAN SA (CH) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10640460-B2 | Substituted cyclopentyl- and cyclohexyl-derivatives useful for perfumery | C5, ACLY, CBR3 | ALDH1A1 545/4885TRPM8 760/4885NPSR1 228/4885 |
| US-20180346412-A1 | SUBSTITUTED CYCLOPENTYL- AND CYCLOHEXYL-DERIVATIVES USEFUL FOR PERFUMERY | C5, ACLY, CBR3 | ALDH1A1 545/4885TRPM8 760/4885NPSR1 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.