Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | ESRRB | O95718 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17554782 | 0.89 | KMT2A (0.33) | ESRRBESR1ESRRAESRRGESR2 | |
| SCHEMBL18952970 | 0.89 | AR (0.36) | ARESRRBESR1ESRRAESRRG | |
| SCHEMBL1980146 | 0.88 | AR (0.44) | ARESRRBESR1ESRRAESRRG | |
| SCHEMBL18953024 | 0.80 | AR (0.45) | ARESRRBESR1ESRRAESRRG | |
| SCHEMBL1979175 | 0.79 | AR (0.44) | ARESRRBESR1ESRRAESRRG | |
| SCHEMBL18952974 | 0.79 | MMP13 (0.33) | ARESRRBESR1ESRRAESRRG | |
| SCHEMBL13720756 | 0.78 | ELANE (0.34) | ARESRRBESR1ESRRAESRRG | |
| SCHEMBL30939559 | 0.78 | ELANE (0.34) | ARESRRBESR1ESRRAESRRG | |
| SCHEMBL17354637 | 0.76 | AR (0.40) | ARL3MBTL1 | |
| SCHEMBL21610138 | 0.76 | AR (0.39) | ARESRRBESR1ESRRAESRRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386506-A1 | MODULATORS OF KV3 CHANNELS TO TREAT PAIN | Autifony Therapeutics Limited (GB) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017098254-A1 | MODULATORS OF KV3 CHANNELS TO TREAT PAIN | AUTIFONY THERAPEUTICS LIMITED (GB) | 2017-06-15 | — | — | WO | disclosed |