SCHEMBL18952948

SCHEMBL18952948

COC(=O)c1cc2cc(O)c(C(=O)OC)cc2cc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.59
CA1 P00915 5/20 0.59
CA2 P00918 5/20 0.59
CA7 P43166 5/20 0.59
CA9 Q16790 5/20 0.59
CA14 Q9ULX7 5/20 0.59
PDK2 Q15119 1/20 0.59
PDK4 Q16654 1/20 0.59
GAA P10253 2/20 0.55
LMNA P02545 3/20 0.52
TSHR P16473 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.50
KDM4E B2RXH2 4/20 0.48
XDH P47989 2/20 0.48
POLB P06746 1/20 0.48
NFKB1 P19838 1/20 0.48
GFER P55789 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
FUT7 Q11130 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14870982 0.92 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL1109633 0.88 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL30756694 0.88 LMNA (0.60) CA12CA1CA2CA7CA9
SCHEMBL441907 0.88 LMNA (0.60) CA12CA1CA2CA7CA9
SCHEMBL31354651 0.88 LMNA (0.60) CA12CA1CA2CA7CA9
SCHEMBL629964 0.87 CA12 (0.66) CA12CA1CA2CA7CA9
SCHEMBL2735777 0.87 CA12 (0.66) CA12CA1CA2CA7CA9
SCHEMBL30382562 0.87 CA12 (0.66) CA12CA1CA2CA7CA9
SCHEMBL28806041 0.86 LMNA (0.58) CA12CA1CA2CA7CA9
SCHEMBL1538335 0.86 CA12 (0.63) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108699076-B Naphtho-indacenodithiophene and polymers CLAP有限公司 2021-07-16 CN disclosed
US-10793668-B2 Naphthoindacenodithiophenes and polymers CLAP CO., LTD. (KR) 2020-10-06 US disclosed
US-10793668-B2 Naphthoindacenodithiophenes and polymers CLAP CO., LTD. (KR) 2020-10-06 US disclosed
EP-3386989-B1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2019-10-23 EP disclosed
EP-3386989-B1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2019-10-23 EP disclosed
US-20180362704-A1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2018-12-20 US disclosed
EP-3386989-A1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2018-10-17 EP disclosed
WO-2017191466-A1 ORGANIC TERNARY BLENDS IMPERIAL INNOVATIONS LIMITED (GB) 2017-11-09 WO disclosed
WO-2017191468-A1 NON-FULLERENE ELECTRON ACCEPTORS IMPERIAL INNOVATIONS LIMITED (GB) 2017-11-09 WO disclosed
WO-2017097924-A1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2017-06-15 WO disclosed
WO-2017097924-A1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2017-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10793668-B2 Naphthoindacenodithiophenes and polymers RPS21, NR2C2, NR0B2 CA12 1367/4885CA1 3139/4885CA2 3856/4885
US-20180362704-A1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS RPS21, NR2C2, NR0B2 CA12 1367/4885CA1 3139/4885CA2 3856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.