Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 4/20 | 0.43 |
| ▸ | PRNP | P04156 | 3/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691759 | 0.89 | SLC2A1 (0.48) | SLC2A1PRNPNR1H4PSMD14 | |
| SCHEMBL18953132 | 0.88 | SLC2A1 (0.44) | SLC2A1PRNPNR1H4PSMD14KCNK3 | |
| SCHEMBL14632080 | 0.86 | AKT1 (0.43) | SLC2A1KCNK3KCNK9GABRA2GABRB2 | |
| SCHEMBL10175208 | 0.81 | GABRA2 (0.53) | SLC2A1GABRA2GABRB2SLC2A2 | |
| SCHEMBL1691416 | 0.81 | PRNP (0.50) | SLC2A1PRNPPSMD14KCNK3KCNK9 | |
| SCHEMBL1691322 | 0.79 | ALDH1A1 (0.51) | SLC2A1NR1H4PSMD14GABRA2GABRB2 | |
| SCHEMBL1691573 | 0.78 | SLC2A1 (0.52) | SLC2A1PRNPNR1H4PSMD14GABRA2 | |
| Trifluoroacetic Acid SCHEMBL1691777 | 0.77 | SLC2A1 (0.44) | SLC2A1PRNPNR1H4KCNK3KCNK9 | |
| SCHEMBL18977247 | 0.76 | NR1H4 (0.44) | SLC2A1NR1H4GABRA2GABRB2SLC2A2 | |
| Trifluoroacetic Acid SCHEMBL1691729 | 0.76 | GABRA2 (0.50) | SLC2A1GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386494-A1 | VAP-1 INHIBITORS FOR TREATING PAIN | Benevolentai Cambridge Limited (GB) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017098236-A1 | VAP-1 INHIBITORS FOR TREATING PAIN | PROXIMAGEN LIMITED (GB) | 2017-06-15 | — | — | WO | disclosed |