Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TNF | P01375 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954712 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TNFMAPTHTTHSD17B10 | |
| SCHEMBL18954583 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TNFMAPTHTTHSD17B10 | |
| SCHEMBL18954676 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTHTTHSD17B10TSHR | |
| SCHEMBL18954700 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TNFMAPTHTTHSD17B10 | |
| SCHEMBL18954685 | 0.81 | PARK7 (0.58) | ALDH1A1MAPTHTTHSD17B10TSHR | |
| SCHEMBL28527361 | 0.80 | CES1 (0.43) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL18954612 | 0.79 | ALDH1A1 (0.73) | ALDH1A1MAPTHTTHSD17B10TSHR | |
| SCHEMBL18954646 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TNFMAPTHTTHSD17B10 | |
| SCHEMBL18954556 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MAPTHTTHSD17B10TSHR | |
| SCHEMBL18955310 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TNFMAPTHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |