Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 20/20 | 0.71 |
| ▸ | CA2 | P00918 | 20/20 | 0.71 |
| ▸ | CA9 | Q16790 | 20/20 | 0.71 |
| ▸ | CA12 | O43570 | 17/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954786 | 0.84 | CA1 (0.76) | CA1CA2CA9CA12 | |
| SCHEMBL18954710 | 0.84 | CA1 (0.76) | CA1CA2CA9CA12 | |
| SCHEMBL18955274 | 0.83 | CA1 (0.74) | CA1CA2CA9CA12 | |
| SCHEMBL18954634 | 0.81 | CA1 (0.69) | CA1CA2CA9CA12 | |
| SCHEMBL18954669 | 0.81 | CA1 (0.82) | CA1CA2CA9CA12 | |
| SCHEMBL4596097 | 0.81 | TGM2 (0.58) | CA12 | |
| SCHEMBL30132795 | 0.81 | TGM2 (0.58) | CA12 | |
| SCHEMBL18954770 | 0.80 | CA1 (0.69) | CA1CA2CA9CA12 | |
| SCHEMBL18955090 | 0.80 | CA1 (0.69) | CA1CA2CA9CA12 | |
| SCHEMBL18954625 | 0.80 | CA1 (0.69) | CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |