SCHEMBL1895641

SCHEMBL1895641

CCCNC(=O)Oc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.58
NPC1 O15118 1/20 0.58
GAA P10253 1/20 0.58
RAB9A P51151 1/20 0.58
MGLL Q99685 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1891640 0.89 MGLL (0.66) MGLL
SCHEMBL13055389 0.88 TAAR1 (0.60) TAAR1NPC1GAARAB9A
SCHEMBL1456951 0.88 MGLL (0.70) MGLL
SCHEMBL28570445 0.86 MGLL (0.73) MGLL
SCHEMBL21891896 0.86 MGLL (0.73) MGLL
SCHEMBL28333275 0.86 MGLL (0.73) MGLL
SCHEMBL28335638 0.86 MGLL (0.73) MGLL
SCHEMBL22472046 0.86 MGLL (0.73) MGLL
SCHEMBL6757093 0.86 MGLL (0.73) MGLL
SCHEMBL27554564 0.86 MGLL (0.73) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113024418-B Method for synthesizing alicyclic carbamate by using isopropanol as hydrogen source 河北工业大学 2023-01-24 CN claimed
CN-113926403-A Preparation device and method of diphenylmethane dicarbamic acid ester 中国科学院过程工程研究所 2022-01-14 CN claimed
CN-112898184-A Method for continuously synthesizing alicyclic carbamate 河北工业大学 2021-06-04 CN claimed
CN-100491368-C Dioxane-2-alkyl carbamate derivatives SANOFI AVENTIS (FR) 2009-05-27 CN claimed
CN-1777595-A Dioxane-2-alkylcarbamate derivatives, their preparation and their therapeutic use SANOFI AVENTIS (FR) 2006-05-24 CN claimed
CN-1759095-A N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives ELAN PHARM INC (US) 2006-04-12 CN claimed
JP-3167104-A None JP disclosed
CN-119019380-A Benzimidazole-6-sulfonylurea compound and medical application thereof 南京羚诺生物医药技术研究院有限公司 2024-11-26 CN disclosed
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
WO-2023106377-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND 旭化成株式会社 2023-06-15 WO disclosed
CN-112020493-B Method for producing urethane and method for producing isocyanate 旭化成株式会社 2023-04-21 CN disclosed
CN-113024418-B Method for synthesizing alicyclic carbamate by using isopropanol as hydrogen source 河北工业大学 2023-01-24 CN disclosed
WO-2022075347-A1 METHOD FOR PRODUCING OCTAHYDROTHIENOQUINOLINE COMPOUND, AND PRODUCTION INTERMEDIATE OF SAME キッセイ薬品工業株式会社 2022-04-14 WO disclosed
EP-1522540-A1 AZAARENE DERIVATIVES Eisai Co., Ltd. (JP) 2005-04-13 EP disclosed
EP-1506962-A2 Nitrogen-containing aromatic heterocycles Eisai Co. Ltd. (JP) 2005-02-16 EP disclosed
EP-1415987-A1 NITROGENOUS AROMATIC RING COMPOUNDS Eisai Co., Ltd. (JP) 2004-05-06 EP disclosed
US-20040053908-A1 Urea derivatives containing aromatic or heteroaromatic rings, useful as prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective EISAI R&D MANAGEMENT CO., LTD. (JP) 2004-03-18 US disclosed
CN-1478078-A Nitrogen-containing aromatic ring derivatives ������������ʽ���� 2004-02-25 CN disclosed
JP-H03167104-A FLOWERING PROMOTER OF ASPARAGUS MITSUBISHI KASEI CORP 1991-07-19 JP disclosed
US-3938986-A ISOPROPYL N-PHENYLCARBAMATE OR ISOPROPYL N-(3-CHLOROPHENYL)CARBAMATE AND 4-CHLOROPHENYL N-METHYLCARBAMATE PPG INDUSTRIES, INC. (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040053908-A1 Urea derivatives containing aromatic or heteroaromatic rings, useful as prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective VEGFA, UACA, UTS2R TAAR1 2021/4885NPC1 1179/4885GAA 1408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.