SCHEMBL189622

SCHEMBL189622

O=Cc1c(Cl)ccc(Cl)c1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
TDP1 Q9NUW8 3/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
HSD17B10 Q99714 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36
TSHR P16473 1/20 0.34
VCAM1 P19320 1/20 0.33
CYP2A6 P11509 1/20 0.32
CES1 P23141 2/20 0.31
HSP90AA1 P07900 1/20 0.31
ERN1 O75460 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
AHR P35869 1/20 0.31
MAPT P10636 1/20 0.31
ADRA2A P08913 1/20 0.30
PNMT P11086 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21866036 0.82 ALDH1A1 (0.52) ALDH1A1TDP1MEN1KMT2AHSD17B10
SCHEMBL909851 0.80 ALDH1A1 (0.50) ALDH1A1TDP1MEN1KMT2ACYP3A4
SCHEMBL1413983 0.80 CYP3A4 (0.52) ALDH1A1TDP1MEN1KMT2AHSD17B10
SCHEMBL1359343 0.80 ALDH1A1 (0.50) ALDH1A1TDP1MEN1KMT2AHSD17B10
SCHEMBL953875 0.80 ALDH1A1 (0.44) ALDH1A1TDP1MEN1KMT2AHSD17B10
SCHEMBL9005985 0.80 ALDH1A1 (0.44) ALDH1A1TDP1MEN1KMT2AHSD17B10
SCHEMBL677934 0.80 CYP3A4 (0.52) ALDH1A1TDP1MEN1KMT2ACYP3A4
SCHEMBL12760836 0.80 TSHR (0.48) ALDH1A1TDP1MEN1KMT2AHSD17B10
SCHEMBL320653 0.77 ALDH1A1 (0.46) ALDH1A1TDP1MEN1KMT2AHTR2A
SCHEMBL8128591 0.77 TSHR (0.50) ALDH1A1TDP1MEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12234384-B2 Adhesion-improving composition for textile material and associated reinforcing textile material PORCHER INDUSTRIES (FR) 2025-02-25 US claimed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-112135862-B Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2022-06-03 CN claimed
US-20210115310-A1 ADHESION-IMPROVING COMPOSITION FOR TEXTILE MATERIAL AND ASSOCIATED REINFORCING TEXTILE MATERIAL PORCHER INDUSTRIES (FR) 2021-04-22 US claimed
EP-3784719-A1 ADHERENCE-IMPROVING COMPOSITION FOR TEXTILE MATERIAL AND ASSOCIATED REINFORCING TEXTILE MATERIAL Porcher Industries (FR) 2021-03-03 EP claimed
CN-112135862-A Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2020-12-25 CN claimed
WO-2019142208-A1 AMBIENT TEMPERATURE CURABLE NON-ISOCYANATE POLYHYDROXYALKYLURETHANE MOIETIES WITH ALDEHYDE CROSS LINKER Asian Paints Ltd. (IN) 2019-07-25 WO claimed
US-9234087-B2 Preparation for initiating radical reactions UNITED INITIATORS GMBH & CO. KG (DE) 2016-01-12 US claimed
EP-2288652-B1 PREPARATION FOR INITIATING RADICAL REACTIONS UNITED INITIATORS GMBH & CO KG (DE) 2012-09-19 EP claimed
US-20030162963-A1 Novel expanded porphyrins and process for the synthesis thereof JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2003-08-28 US claimed
EP-1306380-A1 NOVEL EXPANDED PORPHYRINS AND PROCESS FOR THE SYNTHESIS THEREOF Japan Science and Technology Corporation (JP) 2003-05-02 EP claimed
WO-2002096849-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2002-12-05 WO claimed
WO-2002083123-A1 AURONES AS TELOMERASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2002-10-24 WO claimed
EP-0827507-B1 PROTEASE INHIBITING SUCCINIC ACID DERIVATIVES BOEHRINGER INGELHEIM CA LTD (CA) 1999-06-16 EP claimed
EP-0827507-A1 PROTEASE INHIBITING SUCCINIC ACID DERIVATIVES BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 1998-03-11 EP claimed
WO-1996031527-A1 PROTEASE INHIBITING SUCCINIC ACID DERIVATIVES BOEHRINGER INGELHEIM (CANADA) LTD./BOEHRINGER INGELHEIM (CANADA) LTÉE. (CA) 1996-10-10 WO claimed
US-5545640-A VIRICIDES, HIV; AIDS BIO-MEGA/BOEHRINGER INGELEHEIM RESEARCH INC. (CA) 1996-08-13 US claimed
US-4868241-A POLYVINYL ALCOHOL MODIFIED WITH BENZOIC ACID DERIVATIVE AMERICAN CYANAMID COMPANY (US) 1989-09-19 US claimed
EP-0231922-A2 Electron beam and X-ray resists AMERICAN CYANAMID COMPANY (US) 1987-08-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162963-A1 Novel expanded porphyrins and process for the synthesis thereof AAAS, PAM, AHR ALDH1A1 3008/4885TDP1 4734/4885MEN1 952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.