SCHEMBL1896477

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12662491	0.94	PARP1 (0.43)	PARP1WDR5ALKPTGESENPP2
	SCHEMBL12662733	0.89	PARP1 (0.44)	PARP1WDR5ALKENPP2GCK
	SCHEMBL3695576	0.88	WDR5 (0.42)	WDR5ALKENPP2GCK
	SCHEMBL12662672	0.86	PARP1 (0.51)	PARP1ALKENPP2GCKTRPV4
	SCHEMBL4548005	0.85	WDR5 (0.40)	WDR5ALKENPP2GCKTRPV4
	SCHEMBL12662731	0.83	PARP1 (0.46)	PARP1WDR5ALKGCKTRPV4
	SCHEMBL13257076	0.83	WDR5 (0.42)	WDR5ALKPTGESENPP2GCK
	SCHEMBL12662739	0.83	PARP1 (0.44)	PARP1WDR5ALKGCKTRPV4
	SCHEMBL12662725	0.82	GCK (0.47)	PARP1GCKTRPV4
	SCHEMBL4547993	0.82	WDR5 (0.40)	WDR5ALKENPP2GCKTRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.