⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468215 | 1.00 | — | — | |
| SCHEMBL29416264 | 1.00 | — | — | |
| Bicarbonate SCHEMBL20894929 | 0.95 | ALDH1A1 (0.36) | — | |
| Succinamide SCHEMBL28745278 | 0.90 | SOAT1 (0.33) | — | |
| SCHEMBL8955959 | 0.79 | ALDH1A1 (0.37) | — | |
| SCHEMBL8531695 | 0.78 | — | — | |
| SCHEMBL28819476 | 0.78 | LMNA (0.31) | — | |
| SCHEMBL14795248 | 0.78 | — | — | |
| SCHEMBL1515332 | 0.77 | — | — | |
| SCHEMBL16058445 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220081401-A1 | SELECTIVE ANDROGEN RECEPTOR DEGRADER (SARD) LIGANDS AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2022-03-17 | — | — | US | disclosed |
| US-20170166526-A1 | SELECTIVE ANDROGEN RECEPTOR DEGRADER (SARD) LIGANDS AND METHODS OF USE THEREOF | ONCTERNAL THERAPEUTICS, INC | 2017-06-15 | — | — | US | disclosed |