SCHEMBL18965462

SCHEMBL18965462

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(-c6cccc7cc(-c8ccc(-c9nc(-c%10ccccc%10)nc(-c%10ccc%11ccccc%11c%10)n9)cc8)ccc67)cccc5c4)cc3)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
TP53 P04637 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CYP1A2 P05177 2/20 0.46
HSD17B1 P14061 4/20 0.45
HSD17B2 P37059 4/20 0.45
ESR1 P03372 5/20 0.43
ESR2 Q92731 5/20 0.43
CYP17A1 P05093 1/20 0.42
CYP19A1 P11511 1/20 0.42
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
PIM1 P11309 1/20 0.42
MAPT P10636 4/20 0.42
HPGD P15428 3/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23633511 0.95 ALDH1A1 (0.45) ALDH1A1KDM4EMEN1KMT2ATP53
SCHEMBL17655851 0.95 HSD17B1 (0.47) ALDH1A1KDM4EMEN1KMT2ATP53
SCHEMBL18965445 0.94 MEN1 (0.50) ALDH1A1KDM4EMEN1KMT2ATP53
SCHEMBL18965464 0.94 MEN1 (0.50) ALDH1A1KDM4EMEN1KMT2ATP53
SCHEMBL25680783 0.94 ALDH1A1 (0.44) ALDH1A1KDM4EMEN1KMT2ATP53
SCHEMBL24377056 0.94 HSD17B1 (0.48) ALDH1A1KDM4EMEN1KMT2ATP53
SCHEMBL24377091 0.94 HSD17B1 (0.45) ALDH1A1KDM4EMEN1KMT2ATP53
SCHEMBL18965493 0.94 HSD17B1 (0.49) ALDH1A1KDM4EMEN1KMT2ATP53
SCHEMBL21667499 0.92 ALDH1A1 (0.45) ALDH1A1KDM4EMEN1KMT2ATP53
SCHEMBL17655824 0.92 HSD17B1 (0.47) ALDH1A1KDM4EMEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017099430-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2017-06-15 WO disclosed