SCHEMBL18965686

SCHEMBL18965686

Cc1ccc2c(ccc3c4ccc(N)cc4ccc23)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.59
HSD17B10 Q99714 4/20 0.59
KDM4E B2RXH2 4/20 0.59
LMNA P02545 2/20 0.59
HPGD P15428 2/20 0.59
GAA P10253 1/20 0.59
CYP2A6 P11509 4/20 0.50
CYP1A2 P05177 3/20 0.50
ACHE P22303 1/20 0.44
PLAU P00749 2/20 0.44
NCK1 P16333 1/20 0.44
BACE1 P56817 1/20 0.44
POLB P06746 1/20 0.44
CASP6 P55212 1/20 0.44
TDP1 Q9NUW8 4/20 0.43
CYP3A4 P08684 3/20 0.43
ALOX15 P16050 2/20 0.41
CASP1 P29466 2/20 0.41
CASP7 P55210 1/20 0.41
HBB P68871 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL806511 0.86 CYP2A6 (0.68) ALDH1A1HSD17B10KDM4ELMNAHPGD
SCHEMBL8121539 0.86 ALDH1A1 (0.55) ALDH1A1HSD17B10KDM4ELMNAACHE
SCHEMBL597341 0.86 CYP1A2 (0.67) ALDH1A1HSD17B10KDM4ELMNAHPGD
SCHEMBL13293000 0.84 CYP2A6 (0.70) ALDH1A1HSD17B10KDM4ELMNAHPGD
SCHEMBL607927 0.83 CYP1A2 (0.71) ALDH1A1HSD17B10KDM4ELMNAHPGD
SCHEMBL2445157 0.83 ALDH1A1 (0.57) ALDH1A1HSD17B10KDM4ELMNAHPGD
SCHEMBL5748980 0.82 ALDH1A1 (0.62) ALDH1A1HSD17B10KDM4ELMNAHPGD
SCHEMBL5747119 0.82 ALDH1A1 (0.62) ALDH1A1HSD17B10KDM4ELMNAHPGD
SCHEMBL4925789 0.79 ALDH1A1 (0.60) ALDH1A1HSD17B10KDM4ELMNAHPGD
SCHEMBL25656333 0.77 ALDH1A1 (0.47) ALDH1A1HSD17B10KDM4ELMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3551635-B1 THIENO-INDENO-MONOMERS AND POLYMERS BASF SE (DE) 2021-04-28 EP disclosed
EP-3166949-B1 THIENOTHIOPHENE-ISOINDIGO CLAP CO LTD (KR) 2021-02-17 EP disclosed
EP-3386989-B1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2019-10-23 EP disclosed
WO-2018104367-A2 THIENO-INDENO-MONOMERS AND POLYMERS BASF SE (DE) 2018-06-14 WO disclosed
WO-2017097924-A1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2017-06-15 WO disclosed