SCHEMBL806511

SCHEMBL806511

Cc1ccc2cc(N)ccc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.68
CYP1A2 P05177 3/20 0.68
ALDH1A1 P00352 8/20 0.56
TDP1 Q9NUW8 5/20 0.56
HSD17B10 Q99714 3/20 0.56
CYP3A4 P08684 3/20 0.56
ALOX15 P16050 2/20 0.54
CASP1 P29466 2/20 0.54
CASP7 P55210 1/20 0.54
HBB P68871 1/20 0.54
HIF1A Q16665 1/20 0.54
ACHE P22303 1/20 0.52
KDM4E B2RXH2 3/20 0.52
MAPT P10636 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
LMNA P02545 2/20 0.50
POLB P06746 2/20 0.50
NCK1 P16333 1/20 0.50
BACE1 P56817 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5748980 0.95 ALDH1A1 (0.62) CYP2A6CYP1A2ALDH1A1TDP1HSD17B10
SCHEMBL5747119 0.95 ALDH1A1 (0.62) CYP2A6CYP1A2ALDH1A1TDP1HSD17B10
SCHEMBL13293000 0.92 CYP2A6 (0.70) CYP2A6CYP1A2ALDH1A1TDP1HSD17B10
SCHEMBL18965686 0.86 ALDH1A1 (0.59) CYP2A6CYP1A2ALDH1A1TDP1HSD17B10
SCHEMBL29367325 0.83 ALDH1A1 (0.77) ALDH1A1TDP1HSD17B10CYP3A4ALOX15
SCHEMBL308248 0.83 CYP1A2 (1.00) CYP2A6CYP1A2ALDH1A1TDP1HSD17B10
SCHEMBL145891 0.83 ALDH1A1 (0.77) ALDH1A1TDP1HSD17B10CYP3A4ALOX15
SCHEMBL29389285 0.83 CYP1A2 (1.00) CYP2A6CYP1A2ALDH1A1TDP1HSD17B10
SCHEMBL23183328 0.81 CYP2A6 (0.56) CYP2A6CYP1A2ALDH1A1TDP1HSD17B10
Naphthylamine SCHEMBL11217490 0.81 ALDH1A1 (0.74) CYP2A6CYP1A2ALDH1A1TDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041272-B Benzoxazole derivative and synthesis method thereof 陕西科技大学 2024-09-03 CN claimed
CN-115260122-B Naphthothiazole derivative and synthesis method thereof 陕西科技大学 2024-05-28 CN claimed
CN-115368292-B Benzondoles compound and synthesis method thereof 陕西科技大学 2024-05-10 CN claimed
CN-116041272-A Benzoxazole derivative and synthesis method thereof 陕西科技大学 2023-05-02 CN claimed
CN-115368292-A Benzoindole compound and synthetic method thereof 陕西科技大学 2022-11-22 CN claimed
CN-115260122-A Naphthothiazole derivative and synthesis method thereof 陕西科技大学 2022-11-01 CN claimed
CN-104230728-B 1,2-diketone naphthalene compounds and preparation method and application 山东大学 2016-08-24 CN claimed
WO-2026090321-A1 TREATMENT OF CANCER WITH A KRAS INHIBITOR ALTEROME THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
CN-116041272-B Benzoxazole derivative and synthesis method thereof 陕西科技大学 2024-09-03 CN disclosed
CN-115260122-B Naphthothiazole derivative and synthesis method thereof 陕西科技大学 2024-05-28 CN disclosed
CN-115368292-B Benzondoles compound and synthesis method thereof 陕西科技大学 2024-05-10 CN disclosed
EP-3912983-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-15 EP disclosed
WO-2023212818-A1 DYES FOR MONITORING CELL STATES Sunnybrook Research Institute (CA) 2023-11-09 WO disclosed
US-4209593-A Semi-flexible shock-absorbing polyurethane foam prepared from a triol, a compound having a single reactive hydrogen, an aromatic polyisocyanate, blowing agent, chain-extender and a catalyst UNIROYAL LTD. (CA) 1980-06-24 US disclosed
EP-0010842-A1 Polyurethane foam and method of preparation thereof UNIROYAL LTD. (CA) 1980-05-14 EP disclosed
US-4116952-A POLYAMIDES CIBA-GEIGY CORPORATION (US) 1978-09-26 US disclosed
US-4033942-A Chromium complex dye, including azo and azo methine dye compounds CIBA-GEIGY AG (CH) 1977-07-05 US disclosed
US-3978037-A POLYAMIDES CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US disclosed