Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24908194 | 0.84 | CYP17A1 (0.50) | CA12CA1CA9CYP17A1NAMPT | |
| SCHEMBL13885934 | 0.83 | CYP17A1 (0.50) | CA12CA1CA9CYP17A1PSMB8 | |
| SCHEMBL7477384 | 0.77 | CA12 (0.48) | CA12CA1CA9CYP17A1PSMB8 | |
| SCHEMBL20226398 | 0.77 | LMNA (0.53) | CA12CA1CA9CYP17A1PSMB8 | |
| SCHEMBL16302366 | 0.77 | CA12 (0.51) | CA12CA1CA9CYP17A1PSMB8 | |
| SCHEMBL19037775 | 0.76 | SMN1; SMN2 (0.39) | CA1NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL13055402 | 0.75 | CYP17A1 (0.59) | CA12CA1CA9CYP17A1PSMB8 | |
| SCHEMBL19826504 | 0.75 | LCK (0.45) | CA12CA1CA9CYP17A1PSMB8 | |
| SCHEMBL10305747 | 0.75 | MAP4K4 (0.46) | CA12CA1CA9CYP17A1PSMB8 | |
| SCHEMBL1689760 | 0.75 | CA12 (0.43) | CA12CA1CA9CYP17A1PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9958452-B2 | Highly fluorogenic protein labelling agents | UNIVERSITY OF OTTAWA (CA) | 2018-05-01 | — | — | US | disclosed |
| US-20170168064-A1 | HIGHLY FLUOROGENIC PROTEIN LABELLING AGENTS | UNIVERSITY OF OTTAWA (CA) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170168064-A1 | HIGHLY FLUOROGENIC PROTEIN LABELLING AGENTS | IK, PFDN2, FABP2 | CA12 2714/4885CA1 2593/4885CA9 4146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.